figure 2 common targeting agents and ways to improve their affinity and selectivity a the panel shows a variety of targeting molecules such as a monoclonal antibody or antibodies fragments non antibody ligands and aptamers the antibody fragments f ab
... are all the tonal values from black (left) to white of storing exponentially more information (right) The height or shapes ofthe peaks and than the left half WAY more information valleys, for ... The time of capture was almost identi- was still too fast for what I was after, as it cal, the timing ofthe capture wasn’t! was very bright that day So I put on my variable neutral density filter ... conscious of how lines and just a snap-shooter Take charge: be the director of photography, and is the author ofThe shapes direct attention, and use that to your advantage your photographs andof your...
... write a reasonable version for all the clients of your class Otherwise, you force every user of your class to use the properties in your class and create a reasonable human-readable representation ... problems If customer is a value type, a copy of c1 gets stored in the hash map The last line changing the value ofthe name has no effect on the copy stored in the hash map Because boxing and unboxing ... string to indicate the general format If you add support for the IFormattable interface and not support these standard formats, you’ve broken the automatic string conversions in the BCL You can see...
... operator new (including the one you'll find in Item 10) are designed for a specific class, not for a class or any of its subclasses That is, given an operator new for a class X, the behavior of ... propagating the exception Assuming the global operator new was able to successfully allocate enough memory for an object of type X, X's operator new will again call the standard set_new_handler to ... made available Install a different new-handler If the current new-handler can't make any more memory available, perhaps it knows ofa different new-handler that is more resourceful If so, the...
... description and are therefore full of difficult vocabulary and don't have a clear story line yet to help you understand what is happening andto motivate you to turn the next page If the book is still too ... dictionaries are not as good as paper ones for the amount of information they give you about each word, some of them have the very useful function of saying the word with the correct pronunciation ... you may never hear or get the chance to say exactly that line, having one memorable example of an English grammatical form in your head can make it much easier to learn other examples ofthe same...
... potential customers (If you can't stand the thought of leaving any awards out, create a separate "Industry Awards" page and get all crazy with your self-congratulatory self.) So if you won a Tony award, ... About Us pages: Generally speaking, the smaller the business the "fluffier" the content Fluff is boring Candor is compelling Be who you really are and make that your advantage If you're a start-up, ... with a 0021% error rate for the past five years" means a lot because it means you care about, measure, and deliver a service critical to my business Think f act s, not superlat ives Many About...
... antivirus and antispyware programs offer automatic updating Enable that feature so your software always has the most current signatures If automatic updates aren’t offered, be sure to install the software ... go to your software vendors’ websites and check for and install all available updates Enable automatic updates if your vendors offer it; that will ensure your software is always updated, and ... Software Updates and Enable Future Automatic Updates Most software vendors release updates to patch or fix vulnerabilities, flaws, and weaknesses (bugs) in their software Because intruders can...
... phosphorylation was observed, which began 120 after the HAT stimulation and lasted until 480 after treatment (Fig 4A) In order to assess the effect of HAT on the kinase activity of ERK, phosphorylation ... Kawano S, Tsuchihashi S, Ogawara M, Masuda K, Yamaoka K, Takahashi M & Sano T (1997) Purification, characterization, and localization ofa novel trypsin-like protease found in the human airway Am ... Induction of MUC2 and MUC5AC mucins by factors ofthe epidermal growth factor (EGF) family is mediated by EGF receptor ⁄ Ras ⁄ Raf ⁄ extracellular signal-regulated kinase cascade and Sp1 J Biol...
... samples are further stratified by whether or not reservists discharged their weapon in combat (data available from authors) Fair or poor assessment of health based on the SF-36 were comparable for ... for 'GHQ caseness' (score ≥ 3) were selected for interview, together with a random sample ofthe non- GHQ cases Cases were over-sampled; 70% ofthe final sample for the study were GHQ cases, and ... in collaboration with fellow authors, conducted a proportion ofthe interviews, assisted with the planning ofthe analysis, and prepared the first draft of this article for submission LVS assisted...
... as data: the name ofa customer, the x,y location ofa point, or last year’s revenue Properties enable you to create an interface that acts like data access but still has all the benefits ofa ... uses an old style cast rather than theas operator Using the old style cast means that Cast does not need to have a class constraint Using theas operator would be limiting, and rather than ... Data Members Prefer readonly to const Prefer the is oras Operators to Casts Use Conditional Attributes Instead of #if Always Provide ToString() Understand the Relationships Among the Many Different...
... method to achieve the same level of flexibility that named and optional parameters provide Remember that some oftheOf ce APIs have as many as 16 parameters, and optional and named parameters are a ... instance ofa type: Static variable storage is set to Static variable initializers execute Static constructors for the base class execute The static constructor executes Instance variable storage ... parameters at the call site That means the names of formal parameters are now part ofthe public interface for your type Changing the name ofa public parameter could break calling code That means...
... reasonable set of constructors is often the simplest approach You can also create factory methods to initialize the structure Factories make it easier to create common values The NET Framework ... types that are all 0s If possible, make the all case the natural default Asa special case, enums used as flags should ensure that is the absence of all flags Item 20: Prefer Immutable Atomic Value ... tasks and adds a hook for derived classes to free resources they allocate The base class contains the code for the core interface The virtual function provides the hook for derived classes to...
... Serializable ❘ 163 andthe order ofthe variables The order is the order declared in the class (By the way, this fact means that rearranging the order of variables in a class or renaming variables ... base class In some rare cases, you will want to replace the default behavior instead of calling the base class version so that none ofthe event handlers gets called You can’t guarantee that all ... that it can be a serializable base class, you change the serializable constructor to protected and create a virtual method that derived classes can override to store their data: using global::System.Runtime.Serialization;...
... you to perform any processing after the task has finished running In the RunAsync method, it calls the taskFinisher, giving the Task object asthe parameter That enables the caller to perform any ... results available immediately You can request full buffering, which will increase performance at a cost of higher latency Auto Buffering, the default, provides a balance between latency and performance ... continue to be From the Library of Wow! eBook 220 ❘ Chapter Working with the Framework more important as more of our programs must access data on different machines and more threads are waiting for...
... abstractions for the product Those different abstractions may not have the same names for their properties, and they certainly won’t have the same base class or implement the same interface The classic answer ... form ofa base class, a set of interfaces, orthe special constraints for reference type, value type, andthe existence ofa public parameterless constructor You can’t specify that some 227 From ... what to when you want to work with different anonymous types that may have properties ofthe same name but aren’t part of your core application and don’t warrant the work to create a new named...